2021-22 NFL Picks Against the Spread: Week 16

The MikesPickz NFL Picks are back again for the 2021-22 season.

As usual, I will make my picks for each game, every week of the NFL season using the point spread from the NY Daily News on Wednesday. After each week, the post will be updated with the results. My full pick record for all seasons can be found on the historical picks page.

The favorite will be marked with the spread in parenthesis next to the team name. For example, Patriots (-6.5). My best bet is the team that I feel is most likely to win and cover the spread this week.

Welcome to Week 16 of the NFL Season! Without further adieu, here are my picks:

Week 16 BYE WEEKS: None
Best Bet: Bengals (-2.5) – WIN
Week 16 Recap: 9-7-0, 1-0 Best Bet, 1-1 Survivor pool

Thursday Game:

  • 49ers (-3) at Titans
    • The pick: 49ers (-3) – LOSS

Christmas Saturday Games:

  • Browns at Packers (-7.5)
    • The pick: Browns (+7.5) – WIN
  • Colts at Cards (-2)
    • The pick: Colts (+2) – WIN

Sunday Early Games:

  • Bills at Patriots (-2.5)
    • The pick: Bills (+2.5) – WIN
  • Rams (-2.5) at Vikings
    • The pick: Vikings (+2.5) – LOSS
  • Lions at Falcons (-3)
    • The pick: Falcons (-3) – WIN
  • Ravens at Bengals (-2.5)
    • The pick: Bengals (-2.5) – BEST BET – WIN
  • Giants at Eagles (-9.5)
    • The pick: Giants (+9.5) – LOSS
  • Bucs (-11) at Panthers
    • The pick: Panthers (+11) – LOSS
  • Jaguars at Jets (-2.5)
    • The pick: Jaguars (+2.5) – LOSS
  • Chargers (-9.5) at Texans
    • The pick: Chargers (-9.5) – LOSS

Sunday Late Games:

  • Bears at Seahawks (-7)
    • The pick: Bears (+7) – WIN
  • Broncos at Raiders (-2)
    • The pick: Raiders (-2) – WIN
  • Steelers at Chiefs (-10)
    • The pick: Steelers (+10) – LOSS

Sunday Night Football:

  • Football Team at Cowboys (-10)
    • The pick: Cowboys (-10) – WIN

Monday Night Football:

  • Dolphins at Saints (-3)
    • The pick: Dolphins (+3) – WIN

Previous Week’s Record: 7-8-1

Regular Season Record: 121-99-4 (54.91%)

Postseason Record: N/A

Best Bet Record: 7-7-1

Last Season’s Record: 137-119-0 (53.52%)

Click here for my Full Historical Pick Records


King of the Hill aka Lock of the Week aka Survivor Pool Picks:
In this section, I will post my pick for a survivor pool. Once a team is used, I can’t use them again for the rest of the season. The team selected only has to win the game, not cover the spread. Pick One and Pick Two are independent of each other. If I use a team with Pick One, I can use them later with Pick Two.

Week Pick One Pick Two
Week 1 Rams – win Vikings – loss
Week 2 Browns – win Packers – win
Week 3 Broncos – win Panthers – win
Week 4 Saints – loss Bills – win
Week 5 Vikings – win Raiders – loss
Week 6 Colts – win Rams – win
Week 7 Packers – win Cardinals – win
Week 8 Bengals – loss Chiefs – win
Week 9 Bills – loss Cowboys – loss
Week 10 Cowboys – win Colts – win
Week 11 49ers – win Browns – win
Week 12 Patriots – win Eagles – loss
Week 13 Bucs – win Dolphins – win
Week 14 Seahawks – win Broncos – win
Week 15 Cardinals – loss 49ers – win
Week 16 Chargers – loss Bengals – win
Week 17
Week 18
Total 11-5 12-4
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