2024-25 NFL Picks Against the Spread: Week 16

The MikesPickz NFL Picks are back again for the 2024-25 season.

As usual, I will make my picks for each game, every week of the NFL season using the point spread from the NY Daily News on Wednesday. After each week, the post will be updated with the results. My full pick record for all seasons can be found on the historical picks page.

The favorite will be marked with the spread in parenthesis next to the team name. For example, Patriots (-6.5). My best bet is the team that I feel is most likely to win and cover the spread this week.

Welcome to Week 16 of the NFL Season! Without further adieu, here are my picks:

Week 16 BYE WEEKS: None
Best Bet: Bengals (-7.5) – win
Week 16 Recap: 8-8-0, 1-0 Best Bet, 0-0 Survivor pool

Thursday Night Football:

  • Broncos at Chargers (-3)
    • The pick: Chargers (-3) – WIN

Saturday Football:

  • Texans (-1.5) at Chiefs
    • The pick: Chiefs (+1.5) – WIN
  • Steelers at Ravens (-6.5)
    • The pick: Steelers (+6.5) – LOSS

Sunday Early Games:

  • Cardinals (-4.5) at Panthers
    • The pick: Cardinals (-4.5) – LOSS
  • Eagles (-3.5) at Commanders
    • The pick: Eagles (-3.5) – LOSS
  • Lions (-6.5) at Bears
    • The pick: Lions (-6.5) – WIN
  • Giants at Falcons (-9.5)
    • The pick: Giants (+9.5) – LOSS
  • Titans at Colts (-3.5)
    • The pick: Colts (-3.5) – WIN
  • Browns at Bengals (-7.5)
    • The pick: Bengals (-7.5) – BEST BET – WIN
  • Rams (-3) at Jets
    • The pick: Jets (+3) – LOSS

Sunday Late Games:

  • Vikings (-3.5) at Seahawks
    • The pick: Seahawks (+3.5) – WIN
  • Jaguars at Raiders (-1.5)
    • The pick: Jaguars (+1.5) – LOSS
  • Patriots at Bills (-14.5)
    • The pick: Patriots (+14.5) – WIN
  • 49ers at Dolphins (-1.5)
    • The pick: 49ers (+1.5) – LOSS

Sunday Night Football:

  • Bucs (-3.5) at Cowboys
    • The pick: Bucs (-3.5) – LOSS

Monday Night Football:

  • Saints at Packers (-13.5)
    • The pick: Packers (-13.5) – WIN

Previous Week’s Record: 9-7-0

Regular Season Record: 115-109-0 (51.34%)

Postseason Record: N/A

Best Bet Record: 8-7

Last Season’s Record: 146-106-0 (54.60%)

Click here for my Full Historical Pick Records


King of the Hill aka Lock of the Week aka Survivor Pool Picks:
In this section, I will post my pick for a survivor pool. Once a team is used, I can’t use them again for the rest of the season. The team selected only has to win the game, not cover the spread. Pick One and Pick Two are independent of each other. If I use a team with Pick One, I can use them later with Pick Two.

Week Pick One Pick Two
Week 1 Bengals – loss Seahawks – win
Week 2 Texans – win Chargers – win
Week 3 Bucs – loss Browns – loss
Week 4 Jets – loss 49ers – win
Week 5 Seahawks – loss Bears – win
Week 6 Eagles – win Packers – win
Week 7 Commanders – win Bills – win
Week 8 Broncos – win Lions – win
Week 9 Ravens – win Bengals – win
Week 10 Chargers – win Eagles – win
Week 11 Dolphins – win Jets – loss
Week 12 Chiefs – win Dolphins – win
Week 13 Vikings – win Commanders – win
Week 14 Saints – win Bucs – win
Week 15 Cardinals – win Ravens – win
Week 16 Packers – win Cardinals – loss
Week 17
Week 18
Total 12-4 13-3
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